mPopTag | Research

mPopTag: The Multi-Population Tag SNP Picker

The Multi-Population Tag Single Nucleotide Polymorphism (SNP) Picker (mPopTag) is a tool used to select or evaluate linkage disequilibrium (LD) tag SNPs for multiple populations. The program analyzes patterns of LD--measured by composite linkage disequilibrium (CLD) or r2--between polymorphic sites in a genome region for multiple populations. It also uses a greedy algorithm to select a single set of near-minimum numbers of LD tag SNPs for multiple populations.

Downloads

Linux Binary:
mpoptag_linux.zip (3.82 MB)
Software Manual
Source code: please contact

Credits

The mPopTag was developed in and is maintained at the by Zongli Xu, Norman L. Kaplan and Jack A Taylor.

Reference

Xu Z, Kaplan NL, Taylor JA. Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data. Eur J Hum Genet 2007 Oct;15(10):1063-70.

Installation

It can be run on Linux operating system.

Contact

Jack A. Taylor, M.D., Ph.D. (Retired) Scientist Emeritus Tel 984-287-3684 taylor@niehs.nih.gov

Zongli Xu, Ph.D. Staff Scientist Tel 984-287-3730 Fax 301-480-3290 xuz@niehs.nih.gov

Biostatistics & Computational Biology Branch SNPinfo Web Server