Yavin Shaham

0010050432.jpg
Senior Investigator, Behavioral Neuroscience Research Branch, Neurobiology of Relapse Section, National Institute on Drug Abuse (NIDA)

Research Topics

We use rat models to study the cellular and neuroanatomical mechanisms that underlie relapse to drug and aggression seeking (Yavin Shaham group). We also study neurophysiological mechanisms of addictive drugs and motivated behavior (Eugene Kiyatkin group).

Selected Publications

  1. Venniro M, Zhang M, Caprioli D, Hoots JK, Golden SA, Heins C, Morales M, Epstein DH, Shaham Y. Volitional social interaction prevents drug addiction in rat models. Nat Neurosci. 2018;21(11):1520-1529.

  2. Badiani A, Belin D, Epstein D, Calu D, Shaham Y. Opiate versus psychostimulant addiction: the differences do matter. Nat Rev Neurosci. 2011;12(11):685-700.

  3. Venniro M, Banks ML, Heilig M, Epstein DH, Shaham Y. Improving translation of animal models of addiction and relapse by reverse translation. Nat Rev Neurosci. 2020;21(11):625-643.

  4. Venniro M, Russell TI, Ramsey LA, Richie CT, Lesscher HMB, Giovanetti SM, Messing RO, Shaham Y. Abstinence-dependent dissociable central amygdala microcircuits control drug craving. Proc Natl Acad Sci U S A. 2020;117(14):8126-8134.

  5. Fredriksson I, Tsai PJ, Shekara A, Duan Y, Applebey SV, Minier-Toribio A, Batista A, Chow JJ, Altidor L, Barbier E, Cifani C, Li X, Reiner DJ, Rubio FJ, Hope BT, Yang Y, Bossert JM, Shaham Y. Role of ventral subiculum neuronal ensembles in incubation of oxycodone craving after electric barrier-induced voluntary abstinence. Sci Adv. 2023;9(2):eadd8687.