Biostatistics & Computational Biology Branch

Research Summary

The Biostatistics and Computational Biology Branch carries out basic and applied research dealing with statistical issues of relevance to environmental health. The branch's members develop new methodologies and apply existing techniques in novel ways to address environmental health problems. Members of the branch also advise institute scientists on computational, study design, database and statistical issues via both long-term and short-term collaboration in research projects throughout NIEHS. The branch also offers training at regular intervals.

Research in the Biostatistics and Computational Biology Branch focuses on several areas:

• Design and analysis of laboratory animal toxicology/carcinogenicity experiments and development of improved statistical methods
• Application and development of methodology for epidemiological and clinical human studies
• Application and development of new bioinformatics techniques for harvesting information from high-dimensional genomic, gene expression and proteomic data
• Development of new design and analysis approaches in statistical genetics
• Development of broadly applicable statistical approaches

Principal Investigators

Applied Statistics

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Shanshan Zhao, Ph.D. Deputy Chief, Biostatistics & Computational Biology Branch and Principal Investigator Tel 984-287-3702 shanshan.zhao@nih.gov

Bioinformatics

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Leping Li, Ph.D. Principal Investigator Tel 984-287-3836 Fax 919-541-4311 li3@niehs.nih.gov

Computational Systems Biology

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Benedict N. Anchang, M.Sc., Ph.D. Stadtman Investigator Tel 984-287-3350 benedict.anchang@nih.gov

Constrained Statistical Inference

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Shyamal D. Peddada, Ph.D. Principal Investigator Tel 984-287-4586 shyamal.peddada@nih.gov

Integrative Bioinformatics Support Group

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Jianliang Li, Ph.D. Director, Integrative Bioinformatics Support Group Tel 984-287-3626 jianliang.li@nih.gov

Statistical Methods and Applications in Epidemiology

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Clarice R. Weinberg, Ph.D. Principal Investigator Tel 984-287-3697 weinberg@niehs.nih.gov

Statistical Omics

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Alison A. Motsinger-Reif, Ph.D. Chief, Biostatistics & Computational Biology Branch and Principal Investigator Tel 984-287-3705 alison.motsinger-reif@nih.gov

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Mary V. Diaz Santana, Ph.D. Principal Investigator Tel 984-287-3823 mary.diazsantana@nih.gov

Publications

Pandemic vulnerability tool provides county-level snapshots NIEHS mourns passing of statistical geneticist Dmitri Zaykin