Alumni 10 Center Dr, Bethesda, MD, 20814, US 301-496-3064 Epithelial Systems Biology Laboratory (ESBL) The ESBL, led by Mark Knepper, MD, PhD, carries out innovative research on the molecular mechanisms underlying common water-balance disorders, namely dilutional hyponatremia and diabetes insipidus. ESBL researchers integrate state-of-the art proteomics and DNA sequencing methodologies with computational/engineering methods to identify physiological and pathophysiological mechanisms at a cellular level. The Science Research in the Epithelial Systems Biology Laboratory, led by Dr. Mark A. Knepper, concentrates on the physiology and pathophysiology of the kidney, with partic https://pubmed.ncbi.nlm.nih.gov/?term=Knepper+MA&sort=pubdate
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