Muscle Energetics

Alumni 10 Center Dr, Bethesda, MD, 20814, US 301-496-2679 Muscle Energetics The Muscle Energetics Laboratory, led by Dr. Brian Glancy, focuses on how energy is distributed to sustain contractile power in striated muscle cells. Videos

Videos
A fly-through rendering of the mitochondrial network within an oxidative mouse skeletal muscle cell. Mitochondria are colored according to their location relative to the adjacent contractile structures.
Fly-through rendering of the interior structures of a newborn mouse skeletal muscle highlighting cell and organelle membrane as well as myosin filaments.
3D rendering of the interior of a mouse retina mitochondrion. Outer membrane (transparent), inner boundary membrane (transparent), inner membrane cristae (magenta), matrix (yellow), and nucleoids (blue) are shown.
3D rendering of the Z-disk sheets (light green) within the jump muscle of the fruit fly, Drosophila melanogaster. Individual z-disks (various colors) and contractile sarcomeres (magenta) are also shown.
3D rendering of the branching contractile structures within a newborn mouse skeletal muscle. Each color represents an individual myofibril segment. The cell membrane (green) and a nucleus (cyan) are also shown.
3D rendering of the interior of a newborn mouse skeletal muscle. Mitochondria (red), sarcotubular network (green), lipid droplets (yellow), cell membranes (white), and myosin filaments (blue) are shown.

The Science The focus of the Muscle Energetics Laboratory, led by Dr. Brian Glancy, is to determine how mitochondria are optimized within muscle cells to help maintain ener https://scholar.google.com/citations?hl=en&user=xYJyWmYAAAAJ&view_op=list_works&sortby=pubdate