Charcot-Marie-Tooth Disease

The Charcot-Marie-Tooth Disease topic includes research on the genetics, diagnosis, and treatment of this group of inherited conditions that affect peripheral nerves. These nerves carry signals between the brain and spinal cord and the rest of the body, helping control movement and sensation.

Charcot-Marie-Tooth disease can cause muscle weakness and loss of sensations such as pain, touch, heat, and cold. Symptoms often begin in the feet and legs and later affect the hands. The disease can cause trouble with walking, balance, and hand function. Understanding the genetic causes and changes in nerve function can help improve diagnosis and care so people can stay mobile and do their everyday activities.