Emergency Care

Research Areas

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Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) (NIH HEAL Initiative)

Funded by the NIH HEAL Initiative®

This study will evaluate implementation of emergency department (ED)-initiated BUP in a large number of sites; compare extended release (XR)-BUP with sublingual (SL) BUP in ED patients with untreated OUD; and develop and validate electronic health record phenotypes of opioid-related illnesses to characterize ED visits, enhance active disease surveillance, and better identify patients eligible for study inclusion.

NCT04225598

Gail D'Onofrio, M.D., M.S.

Professor of Emergency Medicine