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Estrogen
Reproductive & Developmental Biology Laboratory
Yun-Bo Shi Lab: Section on Molecular Morphogenesis
Unliganded thyroid hormone receptor may play role in development
A novel animal study has uncovered clues to embryo developmental timing and growth rates. The study, recently published in Endocrinology, should prompt further research and improve the understanding on the role of the thyroid hormone (T3) signaling pathway during early development, according to lead author Yun-Bo Shi, PhD, of the Eunice Kennedy Shriver National Institute Child Health and Human Development.
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Jeffrey Baron Lab: Section on Growth and Development
The Section on Growth and Development, headed by Jeffrey Baron MD, investigates the cellular and molecular mechanisms governing childhood growth and development. We focus particularly on growth at the growth plate, which drives bone elongation and therefore determines height. One goal of this work is to gain insight into the many human genetic disorders that cause childhood growth failure or overgrowth. A second goal is to explore the fundamental mechanisms that regulate childhood growth, and a third goal is to develop new treatments for children with severe growth disorders.