Primary Immunodeficiencies

The Primary Immunodeficiencies topic includes research on the causes, diagnosis, prevention, and treatment of primary immunodeficiencies or inborn errors of immunity, which are rare genetic disorders that impair the immune system.

People with a primary immunodeficiency have a dysfunctional immune system, which makes them more likely to get infections and more likely to become very sick from infections. There are more than 400 types of primary immunodeficiencies, and they vary in severity. Treatments can boost the immune system and are tailored to the type of primary immunodeficiency a person has.