Topical Microbicides

The Topical Microbicides topic includes research on the development and evaluation products designed for inserted into the vagina or rectum to prevent transmission of HIV (human immunodeficiency virus) and other sexually transmitted infections, including HIV infection. Topical microbicides come in many different forms, such as gels, creams, films, vaginal rings (also called intravaginal rings or IVRs), and enemas. These products can be applied discreetly before sexual intercourse — an important feature for people who may face stigma or retaliation for using HIV prevention products. Since women and girls in many parts of the world are at particularly high risk for HIV and AIDS (acquired immunodeficiency syndrome), it is especially important for them to have access to their choice of HIV prevention tools, including topical microbicides.