Medical Treatments
Topics
Prescription Opioid Addiction Treatment Study (POATS)
This was a randomized outpatient study for treatment-seeking participants dependent on prescription opioid analgesics. The primary objective was to determine whether the addition of individual drug counseling to the prescription of buprenorphine/naloxone (Bup/Nx) and Standard Medical Management (SMM) improves outcome. Participants were randomized at the beginning of each of two phases to receive BUP/NX paired with either Standard Medical Management (SMM) or Enhanced Medical Management (EMM; defined as SMM plus individual counseling).
Reducing HIV/STD Risk Behaviors: A Research Study for Women in Drug Abuse Treatment
Women in drug-using communities are one of the fastest growing groups of people with AIDS in the U.S. Female drug users, even if they are in drug treatment, are at especially high risk for heterosexual transmission of HIV: they are often in primary sexual relationships with male drug users, some continue to use drugs despite being in treatment, and, under the influence of drugs (especially cocaine or crack) they are more likely to engage in unprotected sex. It has been shown that drug abuse treatment can reduce activities related to drug use that increase the risk of HIV transmission.
Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment
Drug treatment itself can have a powerful positive effect on HIV drug use risk behavior, especially needle use behaviors. However, sexual risk behavior has received less attention and has been shown to be more difficult to change. Research suggests that skills-based HIV risk reduction interventions with peer group discussion and single sex sessions can reduce risky sexual behavior. This study evaluated a five-session HIV risk reduction group therapy designed specifically for men.
A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements into the Electronic Health Record in Large Primary Care Settings
This is a phased feasibility and proof-of-concept study seeking to incorporate addiction-specific screening and assessment CDEs into a widely used EHR, explore the logistics and time required to do this, and assess impacts on the frequency of identification, diagnosis and referral to treatment in large healthcare organizations.
0e472114eda111beae59fb39e136cd55 NCT02963948
NIA-Funded Active Alzheimer’s and Related Dementias Clinical Trials and Studies
The National Institute on Aging (NIA) is currently supporting 466 active clinical trials on Alzheimer’s disease and related dementias (AD/ADRD). These trials reflect diverse drug and mechanistic targets, as well as diversity in the stages of AD/ADRD they address.
Alzheimer Biomarkers Consortium — Down Syndrome (ABC-DS)
Exploring the Connection Between Down Syndrome and Alzheimer's Disease