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Reducing Stigma Toward People with Opioid Use Disorder Among Primary Care Clinicians (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
Randomized, Double-Blind, Placebo-Controlled Trial of Monthly Injectable Buprenorphine for Methamphetamine Use Disorder (MURB)(NIH HEAL Initiative)
Funded by the NIH HEAL Initiative℠
Peer Intervention to Link Overdose survivors to Treatment (PILOT) (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
This study will examine if rapid transition to extended release naltrexone (XR-NTX) following detoxification yields a higher proportion of patients successfully receiving the first injection of XR-NTX compared to standard detoxification and naltrexone initiation and will assess facilitators and barriers to implementing rapid XR-NTX initiation.
NCT04762537
Adam Bisaga, M.D.
Research Psychiatrist
New York State Psychiatric Institute
1051 Riverside Drive, Unit 120 , New York, NY, 10032, US
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE) (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
This study will examine whether 1) in hospitals with addiction medicine consultation services, hospital-initiated extended release buprenorphine (XR-BUP), compared to other OUD medications, results in increased OUD treatment engagement following hospital discharge; and 2) training hospitals without such consultation services on best practices for initiating OUD medication using consultation service hubs improves medication uptake in hospitals and following discharge.
NCT04345718
Optimizing Retention, Duration, and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
This study will 1) test strategies to improve OUD pharmacotherapy treatment retention and to improve outcomes among patients who have been successfully stabilized on OUD medications and want to stop medication; and 2) identify predictors of successful outcome and develop a stage model of relapse risk.
NCT04464980
Edward V. Nunes, Jr., M.D.
Professor of Clinical Psychiatry
Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute
Subthreshold Opioid Use Disorder Prevention (STOP) Trial (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
This study will test the efficacy of a primary care Subthreshold Opioid Use Disorder Prevention (STOP) intervention to reduce unhealthy opioid use and examine the impact of STOP on progression to moderate-severe OUD, overdose risk behavior, and overdose events in adults with unhealthy use of illicit/prescribed opioids.
NCT04218201
Jennifer McNeely, M.D., M.S.
Associate Professor
New York University Grossman School of Medicine
180 Madison Avenue, 17th Floor, New York, NY, 10016, US
Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
Preventing and Identifying Opioid Use Disorder using the Six Building Blocks (6BBs) for Improving Opioid Prescription Management (NIH HEAL Initiative)
Funded by the NIH HEAL Initiative®
This project seeks to develop and test a “train the trainer” curriculum and training experience that will facilitate the spread and use of the Six Building Blocks (6BBs) by adapting the 6BBs framework and toolkit for health systems and other organizations, training personnel to facilitate its implementation, and monitoring results of this implementation
Laura-Mae Baldwin, MD, MPH
Professor
University of Washington
Institute of Translational Health Sciences
Seattle, WA, 98105-4982, US