Substances

Funded by the NIH HEAL Initiative^®

Funded by the NIH HEAL Initiative^®

This study will include analyses of VA databases to examine patient and organizational characteristics associated with buprenorphine termination during outpatient treatment for opioid use disorder. These analyses are critical for generating data and forming further hypotheses on how to implement targeted approaches to improve retention in treatment.

Funded by the NIH HEAL Initiative^®

The goal of the proposed study is to expand the prescription opioid registry developed in study CTN 0061, across diverse health systems with harmonized EHR data, and leverage it to answer several key ‘next step’ research questions in response to the opioid crisis. We propose to adapt and expand the registry to 8 other health systems across the nation, initially within the Health System Node (HSN) to maximize efficiency in the short study timeframe, but with potential to be expanded to other nodes in the future.

Funded by the NIH HEAL Initiative℠

Funded by the NIH HEAL Initiative^®

Using a meta-analytic approach retrospectively analyzing data of individuals with drug use disorders, determine the impact of drug-focused 12-step mutual help groups, free of selection bias, in reducing opioid consumption and opioid-related problems. These data will be used to generate hypotheses on how the augmentation of 12-step mutual help groups, added to medication-assisted treatments (MAT), may be used to improve retention in treatment.

Funded by the NIH HEAL Initiative℠

Investigators will conduct in-depth qualitative interviews exploring experiences with prescription opioid and chronic pain stigma among cancer survivors prescribed opioids for moderate-to-severe chronic pain and caregivers to identify potential contributors to stigma in cancer survivors, with an emphasis on potential targets of future interventions and long-term health outcomes associated with stigma in survivorship.