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Brain Disorders
Topics
- Acquired Cognitive Impairment
- Alzheimer's Disease
- Traumatic Brain Injury (TBI)
- Amyotrophic Lateral Sclerosis (ALS)
- Dementia
- Fetal Alcohol Spectrum Disorders (FASD)
- Transmissible Spongiform Encephalopathy (TSE)
- Frontotemporal Dementia (FTD)
- Multiple Sclerosis
- Anorexia
- Lewy Body Dementia
- Vascular Contributions to Cognitive Impairment & Dementia (VCID)
- Anxiety Disorders
- Aphasia
- Attention-Deficit/Hyperactivity Disorder (ADHD)
- Autism
- Batten Disease
- Bipolar Disorder
- Brain Cancer
- Cerebral Palsy
- Cerebrovascular Health
- Depression
- Down Syndrome
- Eating Disorders
- Epilepsy
- Fragile X
- Huntington's Disease
- Hydrocephalus
- Intellectual & Development Disabilities (IDD)
- Migraines
- Parkinson's Disease
- Post-Traumatic Stress Disorder (PTSD)
- Rett Syndrome
- Schizophrenia
- Stroke
- Tourette Syndrome
- Tuberous Sclerosis
Immunoregulation Section
Arya Biragyn , Ph.D., Chief
Human Neuroscience Section
Dimitrios Kapogiannis , Principal Investigator
Neurocognitive Aging Section
Peter Rapp , Ph.D., Chief
Drug Design and Development Section
Nigel H. Greig , Ph.D., Chief
Transgenics Section
Huaibin Cai , Ph.D., Chief
Our research focuses on elucidating the circuit- and cell-type–specific mechanisms that drive age-related neurodegenerative disorders, with a primary focus on Parkinson’s disease (PD). PD is a rapidly growing neurodegenerative condition that disproportionately affects older adults and manifests not only with progressive motor impairments but also with debilitating non-motor symptoms — such as depression, chronic pain, cognitive decline, and dementia — that remain inadequately treated.
Neuromuscular Diseases Research Section
Bryan J. Traynor , M.D., Ph.D., Chief
The Neuromuscular Diseases Research Section investigates the causes and biology of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our focus is on turning discoveries into better diagnosis and faster development of treatments. We combine large-scale human genetics with detailed molecular profiling to understand disease processes, improve patient grouping, and create biomarkers and outcome tools for clinical trials.
Cardioprotection Section
Steven J. Sollott , MD, Chief
Lipid Peroxidation Unit
Christopher Ramsden , M.D., Ph.D., Chief
Mission
The Lipid Peroxidation Unit leverages expertise in brain lipids and lipoproteins to reveal molecular mechanisms and develop new treatments for age-related diseases, including chronic pain and Alzheimer’s disease.
Brain Aging and Behavior Section
The overall goal of the Brain Aging and Behavior Section (BABS) is to improve cognitive outcomes with aging.
Genome Instability and Chromatin Remodeling Section
Weidong Wang , PhD, Chief